ICML 2025 Past Large language modelsAI for scienceMultimodal

ICML 2025 Workshop on Multi-modal Foundation Models and Large Language Models for Life Sciences

FM4LS 2025

Submission deadline
May 27, 2025, 18:59 UTC
imported from OpenReview — check the website for extensions
Submission portal
OpenReview
Notes
Auto-imported from the OpenReview venue record on 2026-06-10 — please verify and enrich (topics are keyword-guessed).

Accepted papers (69)

Fetched from OpenReview (v2) on 2026-06-10.

  1. 3D-SBDD meets LLM: Towards FDA-Level Drug Design

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  2. A Foundation Model for Mass Spectrometry Proteomics

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  3. A Genomic Language Model for Zero-Shot Prediction of Promoter Indel Effects

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  4. A Look at the Isotropy of Pretrained Protein Language Models

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  5. A Multi-Modal Large Language Model for Free-Form, Open-Ended, and Interactive Prediction of Properties and Mechanisms of Candidate Drug Molecules

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  6. Advancing Knotted Protein Design with ESM3: Guided Generation and Topological Insights

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  7. AIDO.Tissue: Spatial Cell-Guided Pretraining for Scalable Spatial Transcriptomics Foundation Model

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  8. An Interventional Framework of Multimodal Epigenomic Regulation for Gene Expression Prediction

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  9. AnnoDPO: Protein Functional Annotation Learning with Direct Preference Optimization

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  10. ATOMICA: Learning Universal Representations of Intermolecular Interactions

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  11. Benchmarking Vision-Language Contrastive Methods for Medical Representation Learning

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  12. BioLangFusion: Multimodal Fusion of DNA, mRNA, and Protein Language Models

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  13. Cell-Type-Aware Pooling for Robust Sample Classification in Single-Cell RNA-seq Data

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  14. Challenges and Guidelines in Deep Generative Protein Design: Four Case Studies

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  15. Closing the gap between the biology and the clinic with a foundation model of immunology and inflammation

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  16. Conditional Normalizing Flows for the Design of T Cell Therapies

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  17. DeepSeq: High-Throughput Single-Cell RNA Sequencing Data Labeling via Web Search-Augmented Agentic Generative AI Foundation Models

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  18. Describe Anything in Medical Images

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  19. DisProtEdit: Exploring Disentangled Representations for Multi-Attribute Protein Editing

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  20. Enriched Instruction-Following Graph Alignment for Efficient Medical Vision-Language Models

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  21. Evaluating Multi-Modal Models for Enzyme-Reaction Retrieval

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  22. From Vision to Graph Self-Supervised Learning in Digital Pathology

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  23. GeneChat: A Multi-Modal Large Language Model for Gene Function Prediction

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  24. H&Enium, Applying Foundation Models to Computational Pathology and Spatial Transcriptomics to Learn an Aligned Latent Space

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  25. HPP-Voice: A Large-Scale Evaluation of Speech Embeddings for Multi-Phenotypic Classification

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  26. Ibex: Pan-immunoglobulin structure prediction

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  27. Integrating Pathology Foundation Models and Spatial Transcriptomics for Cellular Decomposition from Histology Images

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  28. Joint Diffusion Sampling via Positive-Unlabeled Guidance for Multi-Modal Data

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  29. KD-CPT: A Knowledge-Driven Cellular Phenotypic Transdifferentiation Model

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  30. Knowledge Graph-Augmented DNA Representation Learning

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  31. Learning Diffusion Models with Flexible Representation Guidance

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  32. Leveraging the Structure of Medical Data for Improved Representation Learning

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  33. Ligand Iterative Sampling for Affinity Refinement and Drug Discovery (LISARDD)

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  34. MiST: Understanding the Role of Mid-Stage Scientific Training in Developing Chemical Reasoning Models

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  35. Molecularly informed analysis of histopathology images using natural language

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  36. Multi-Modal Interpretable Graph for Competing Risk Prediction with Electronic Health Records

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  37. Multi-Modal Large Language Model Enables Protein Function Prediction

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  38. Multi-Modal Medical Image Augmentation for Controlled Heterogeneity and Fair Outcomes

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  39. Multi-Objective-Guided Discrete Flow Matching for Controllable Biological Sequence Design

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  40. Multi-Objective-Guided Generative Design of mRNA with Therapeutic Properties

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  41. Multimillion cell self-supervised representation learning enables organ-scale tissue niche discovery

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  42. Multimodal Benchmarking of Foundation Model Representations for Cellular Perturbation Response Prediction

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  43. Multimodal Modeling of CRISPR-Cas12 Activity Using Foundation Models and Chromatin Accessibility Data

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  44. Multimodal Protein Language Models for Flexibility Prediction and Loop Design

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  45. NextGenPLM: A Novel Structure-Infused Foundational Protein Language Model for Antibody Discovery and Optimization

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  46. PM1: A Foundation Model Fusing Genotype, Phenotype, and Image for Precision Medicine

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  47. Promoter Sequence Generation using Homology Prompting

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  48. ProteinAligner: A Tri-Modal Contrastive Learning Framework for Protein Representation Learning

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  49. ProteinGPT: Multimodal LLM for Protein Property Prediction and Structure Understanding

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  50. Rapid and Reproducible Multimodal Biological Foundation Model Development with AIDO.ModelGenerator

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  51. RepoLLM: A Multi-modal Foundation Model for Drug Repurposing via Alignment of Molecules, EHRs, and Knowledge Graphs

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  52. Retrieval Augmented Protein Language Models for Protein Structure Prediction

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  53. Robust Multi-Omics Integration from Incomplete Modalities Significantly Improves Prediction of Alzheimer’s Disease

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  54. Scaling up measurement noise scaling laws

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  55. Segmentation Helps Understanding: Mask-Infused Vision-Language Pre-training for 3D Medical Images

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  56. Self-Supervised Representation Learning for Microbiome Improves Downstream Prediction in Data-Limited Settings and Cross-Cohort Generalizability

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  57. SHIVER: Somatic Hypermutation Informed Vocabulary Encoder Representations

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  58. SOAPIA: Siamese-Guided Generation of Off Target-Avoiding Protein Interactions with High Target Affinity

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  59. Stabilizing protein fitness predictors via the PCS framework

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  60. Temporal Representation Learning for Ultrasound Analysis using Masked Modeling

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  61. TICA-Based Free Energy Matching for Machine-Learned Molecular Dynamics

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  62. Towards foundation models that learn across biological scales

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  63. Towards functional annotation with latent protein language model features

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  64. Towards Molecular Conformer Generation with Language Models

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  65. Transfer Learning of Condition-Specific Perturbation in Gene Interactions: Towards Multi-modal Foundational Modeling of Drug Response

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  66. Transferring Cell-level Drug Response to Patient via Tumor Heterogeneity-Aware Alignment and Gene-level Foundational Models

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  67. TRIDENT: Tri-Modal Molecular Representation Learning with Taxonomic Annotations and Local Correspondence

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  68. Uncertainty-Aware Discrete Diffusion Improves Protein Design

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  69. Unified Representation of Genomic and Biomedical Concepts through Multi-Task, Multi-Source Contrastive Learning

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